KP-3002

CD14-antibody

12307

Background of CD14-antibody

CD14 is a human membrane glycoprotein that plays an important role in the immune system. It is a receptor that is widely present on the surface of monocytes and macrophages, and is involved in the recognition and response of the immune system to bacteria and pathogens. CD14 typically interacts with Toll-like receptors (TLRs) to regulate the activation of immune cells and inflammatory responses.

Specifications

Catalog Number	KP-3002
Antibody Name	CD14-antibody
Isotype	Mouse-IgG1, kappa
Target	CD14
Species Reactivity	Human
Host Cell Line	EXPI-CHO
Purification Method	Affinity purified
Concentration	>2mg/mL
Formulation	20mM sodium citrate,150mM NaCl, pH5.5
Purity	>95% by SDS-PAGE and SEC-SEC-HPLC
Validation	SDS-PAGE \| SEC-HPLC \| ELISA
Endotoxin Level	<0.5 EU/mg as determined by the LAL method
Sterility	0.2μm filtered
Storage	Stable for twelve months from date of receipt when stored at -20°C to -80°C; Stored at 2-8°C for one month without detectable loss of activity.

Characterization

Application

References

Akashi-Takamura, S., and Miyake, K. (2008). TLR accessory molecules. Curr. Opin. Immunol. 20, 420ÿ425.
Baumann, C. L., Aspalter, I. M., Sharif, O., Pichlmair, A., Bluml, S., Grebien, F., et al. (2010). CD14 is a coreceptor of Toll-like receptors 7 and 9. J. Exp. Med. 207, 2689ÿ2701.