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Common Light Chain Antibody

BsAb: Engineered antibody binding two antigens, activating immune cells, inhibiting tumor signaling. Market: $5.8B in 2023, expecting multi-billion growth by 2030.

Heavy Chain Antibody

Cullinan made an initial payment of $25 million and committed up to $600 million in milestone payments, along with a potential royalty of nearly 20% on sales.

Innopedia Database

Innopedia is a robust database designed to provide researchers with enhanced research tools and data support. The database offers browsing, searching, and analytical capabilities for tumor cell lines, engineered cell lines, and standard antibodies.

Ba/F3 Kinase Cell Lines

Kinases regulate nearly all aspects of cellular activities, and alterations in their expression or gene mutations can lead to the development of cancer and other diseases.

Membrane Proteins Screening Array-AB5000

Antibodies, CAR-T cells, and other biopharmaceuticals rely on the specificity of their target binding, which is a critical factor in assessing the quality of these drugs.

New Resource 1

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Document Name

K-ras was the first identified oncogene in the cellular genome, KRAS protein can bind GDP/GTP and possess intrinsic

Document Name

K-ras was the first identified oncogene in the cellular genome, KRAS protein can bind GDP/GTP and possess intrinsic

Document Name

K-ras was the first identified oncogene in the cellular genome, KRAS protein can bind GDP/GTP and possess intrinsic

Document Name

K-ras was the first identified oncogene in the cellular genome, KRAS protein can bind GDP/GTP and possess intrinsic

Document Name

K-ras was the first identified oncogene in the cellular genome, KRAS protein can bind GDP/GTP and possess intrinsic

Document Name

K-ras was the first identified oncogene in the cellular genome, KRAS protein can bind GDP/GTP and possess intrinsic

Document Name

K-ras was the first identified oncogene in the cellular genome, KRAS protein can bind GDP/GTP and possess intrinsic

Document Name

K-ras was the first identified oncogene in the cellular genome, KRAS protein can bind GDP/GTP and possess intrinsic

膜蛋白筛选阵列 AB5000

抗体、CAR-T 细胞及其他生物药的药效与安全性高度依赖其靶点结合特异性,这是评价此类药物质量的关键指标。

Ba/F3 激酶细胞系

激酶几乎调控细胞活动的各个方面,其表达异常或基因突变可导致肿瘤及其他疾病的发生发展。

重链抗体

纳米抗体主要来源于骆驼科动物,因分子量小、易于工程化改造,已成为抗体药物开发领域的研究热点。我们开发了 KY-HC-mouse,这是一种天然缺失轻链、仅产生重链抗体的小鼠模型。

通用轻链抗体

双特异性抗体(BsAb)是治疗多种疾病的有前景的治疗性抗体形式。轻链正确配对是 BsAb 制备过程中的核心问题。为此,我们开发了通用轻链小鼠 KY-CLC-mouse。该小鼠不表达 λ 轻链,并具有一致的 κ 轻链表达。我们已通过开发针对多种抗原、具有统一轻链且高亲和力的不同单克隆抗体,对该小鼠模型进行了验证。

Innopedia 数据库

Innopedia 是一个功能完善的数据库平台,旨在为研究人员提供增强型科研工具与数据支持。该数据库具备浏览、检索和分析功能,可用于肿瘤细胞系、工程化细胞系及标准抗体等资源的查询与研究。